PracticeUpdate: Cardiology - Winter 2018

CONTENTS 5

EDITOR’S PICKS 7 Etripamil Nasal Spray for Rapid

COVER 6

11 Nitroglycerin Injection at the Radial Artery Puncture Site Reduces Occlusion After Transradial Coronary Catheterization 12 Current Smoking Impacts Prognosis After Acute ST-Segment Elevation Myocardial Infarction Comment by James E. Udelson MD 13 Epinephrine vs Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction Comment by Jason N. Katz MD, MHS 14 Home-Based Wearable Continuous ECG Monitoring Patch Improves the Detection of Undiagnosed Atrial Fibrillation Comment by Samuel J. Asirvatham MD, FACC, FHRS, Deepak Padmanabhan MD and Itzhak Z. Attia MS

Conversion of Supraventricular Tachycardia to Sinus Rhythm Comment by Ziad F. Issa MD, MMM 8 Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction: The TOPCAT Trial Comment by Jonathan P. Piccini MD, MHS, FACC, FAHA, FHRS

Prospective Validation of the 0/1-h Algorithm for Early Diagnosis of Myocardial Infarction Comment by Ezra Amsterdam MD

9 Escitalopram vs Placebo Treatment for Depression Improves Long-Term Cardiac Outcomes in Patients With Acute Coronary Syndrome Comment by Viola Vaccarino MD, PhD 10 Regression of Diffuse Ventricular Fibrosis Following Catheter Ablation in Patients With Atrial Fibrillation and Systolic Dysfunction Comment by John M. Miller MD

16 Unmet Need for Adjunctive Dyslipidemia Therapy in Hypertriglyceridemia Management Comment by Peter Libby MD

EXPERT OPINION

17 Clinically Relevant Data on Pioglitazone and CV Risk Reduction Interview with Silvio E. Inzucchi MD

18 Cholesterol, Inflammation and Immunotherapy: Current Implications

20 Drs. Doug Zipes and Jared Bunch Discuss the CABANA Trial

and Future Directions Interview with Peter Libby MD by Jennifer N. Caudle DO

VOL. 3 • NO. 3 • 2018