PracticeUpdate Dermatology Best of 2018

LOOKS CAN BE DECEIVING

IN ATOPIC DERMATITIS

While lesions and itch represent the primary signs and symptoms of atopic dermatitis, hidden signs of inflammation have been shown to persist, even after a flare has subsided. Current evidence suggests that patients’ skin, including nonlesional skin, suffers from chronic subclinical inflammation, a process which is driven by the key Th2 cytokines IL-4 and IL-13. 1–5 Discover what’s really going on beneath the surface.

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atopicdermatitisexposed.com.au

References: 1. Gittler JK, et al. J Allergy Clin Immunol 2012;130(6):1344–1354. 2. Leung DYM, et al. J Clin Invest 2004;113(5):651–657. 3. Suárez Fariñas M, et al. J Allergy Clin Immunol 2011;127(4):954–964. 4. De Benedetto A, et al. J Allergy Clin Immunol 2011;127(3):773–786. 5. Mollanazar NK, et al. Clinic Rev Allerg Immunol 2015. doi:10.1007/s12016-015-8488-5. ©2018 Sanofi. Sanofi-Aventis Australia Pty Ltd trading as Sanofi Genzyme, ABN 31 008 558 807. Talavera Corporate Centre, Building D 12-24 Talavera Road, Macquarie Park, NSW 2113. www.sanofigenzyme.com.au. GZANZ.DUP.17.10.0192 Date of preparation May 2018. SAG0151.

Sanofi Genzyme and Regeneron are committed to providing resources to advance research in dermatology in areas of unmet medical needs among patients with poorly controlled moderate-to-severe atopic dermatitis.