PracticeUpdate Dermatology Best of 2018

EXPERT OPINION 21

References 1. Ogbechie-Godec OA, Wang JF, Feng H, Orlow SJ. High-value dermatology: 5 Laboratory tests to reconsider. J Am Acad Dermatol 2018 Jun;78(6):1232-1235. 2. Winthrop KL, Korman N, Abramovits W, et al. T-cell-mediated immune response to pneumococcal conjugate vaccine (PCV-13) and tetanustoxoid vaccine in patients with moderate-to-severe psoriasis during tofacitinib treatment. J Am Acad Dermatol 2018;78(6):1149- 1155.e1. 3. Lamberts A, Meijer JM, Jonkman MF. Nonbullous pemphigoid: A systematic review. J Am Acad Dermatol 2018;78(5):989-995.e2. 4. Craiglow BG, Boyden LM, Hu R, et al. CARD14- associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris. J Am Acad Dermatol 2018;79(3):487-494. 5. Elder DE, Piepkorn MW, Barnhill RL, et al. Pathologist characteristics associated with accuracy and reproducibility of melanocytic skin lesion interpretation. J Am Acad Dermatol 2018;79(1):52-59.e5. 6. Chasset F, Arnaud L, Jachiet M, et al. Changing antimalarial agents after inefficacy or intolerance in patients with cutaneous lupus erythematosus: A multicenter observational study. J Am Acad Dermatol 2018;78(1):107-114.e1. 7. Choe SJ, Lee S, Pi LQ, et al. Subclinical sensitization with diphenylcyclopropenone is sufficient for the treatment of alopecia areata: Retrospective analysis of 159 cases. J Am Acad Dermatol 2018;78(3):515-521.e4. 8. Beck KM, Yang EJ, Koo J. Dose escalation of doxepin for intractable pruritus. J Am Acad Dermatol 2018;79(3):e37. 9. Amode R, Ingen-Housz-Oro S, Ortonne N, et al. Clinical and histologic features of Mycoplasma pneumoniae-related erythema multiforme: A single-center series of 33 cases compared with 100 cases induced by other causes. J Am Acad Dermatol 2018;79(1):110-117. 10. Kurtzman DJB, Vleugels RA. Anti-melanoma differentiation-associated gene 5 (MDA5) dermatomyositis: A concise review with an emphasis on distinctive clinical features. J Am Acad Dermatol 2018;78(4):776-785. 11. Nelson CA, Noe MH, McMahon CM, et al. Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center. J Am Acad Dermatol 2018;78(2):303-309.e4. 12. Prindaville B, Belazarian L, Levin NA, Wiss K. Pityrosporum folliculitis: A retrospective review of 110 cases. J Am Acad Dermatol 2018;78(3):511-514. 13. Curtiss P, Schwager Z, Cobos G, et al. A systematic review and meta-analysis of the effects of topical nitrates in the treatment of primary and secondary Raynaud's phenomenon. J Am Acad Dermatol 2018;78(6):1110-1118.e3. 14. Chasset F, Tounsi T, Cesbron E, et al. Efficacy and tolerance profile of thalidomide in cutaneous lupus erythematosus: A systematic review and meta-analysis. J Am Acad Dermatol 2018;78(2):342-350.e4. 15. Hashizume H, Fujiyama T, Umayahara T, et al. Repeated Amblyomma testudinarium tick bites are associated with increased galactose-α-1,3- galactose carbohydrate IgE antibody levels: A retrospective cohort study in a single institution. J Am Acad Dermatol 2018;78(6):1135-1141.e3. 16. Lipner SR. Rethinking biotin therapy for hair, nail, and skin disorders. J Am Acad Dermatol 2018 Jun;78(6):1236-1238.

alert the clinician to possible associated interstitial lung disease. Sweet syndrome in patients with and without malignancy 11 Features associated with malignancy include: • Leukopenia, anemia, thrombocytopenia • Absence of arthralgia • Histiocytoid or subcutaneous histopathology Pityrosporum folliculitis 12 Pruritic, fine monomorphic papules and pustules on the face and back in patients previously treated with antibiotics suggest a diagnosis of Pityrosporum folliculitis. Wood’s lamp examination can help estab- lish the diagnosis. Topical nitrates in the treatment of primary and secondary Raynaud’s phenomenon 13 A meta-analysis shows that topical nitrates are effective in treating both primary and secondary Raynaud’s phenomenon.

The pooled rate of thalidomide withdrawal related to adverse events was 24%. Tick bites and red meat allergy 15 Basophils serve as antigen-presenting cells. Sensitization to tick saliva induces allergy to beef, pork, and lamb. Rethinking biotin supplements 16 We commonly ingest biotin: 30 μg/d from egg yolk, milk, nuts, grains, intestinal bacteria. Biotin deficiency is associated with neuro- muscular dysfunction, alopecia, dermatitis. Supplementation is needed in holocar- boxylase synthetase and biotinidase deficiency. The average Western diet contains 35 to 70 μg/d. 5 mg/d may improve atopic dermatitis. 2.5 to 5 mg/d may improve brittle nails, tra- chonychia, and uncombable hair. Downside of biotin supplementation: • Falsely elevated or depressed lab tests – – Thyroid tests – – Troponin www.practiceupdate.com/c/75496

Efficacy and tolerance profile of thalidomide in cutaneous lupus erythematosus 14

The pooled rate of response was 90%, with similar response rates across severe cuta- neous lupus erythematosus subtypes.

VOL. 2 • NO. 4 • 2018