PracticeUpdate Neurology February 2019

CONTENTS 3

RESEARCH Editor’s picks 5 Timing of Anticoagulation After Recent Ischemic Stroke in Patients With Atrial Fibrillation 6 Effect of Nonmyeloablative HSCT vs Continued Disease-Modifying Therapy on Disease Progression in Relapsing– Remitting MS Comment by Erin Longbrake MD

COVER 5

12 Lasmiditan: An Effective Acute Treatment for Migraine 12 Adherence With Psychotherapy and Treatment Outcomes in Patients With Psychogenic Nonepileptic Seizures 13 Diagnostic Sensitivity of Electrophysiology and Ultrasonography in Ulnar Neuropathies of Different Severity Comment by Simon Podnar MD, DSc

Timing of Anticoagulation After Recent Ischemic Stroke in Patients With Atrial Fibrillation

EXPERT OPINION 20 Provocative Induction of Psychogenic

7 Abortion Induces Reactivation of Inflammation in Relapsing–Remitting MS 8 Impact of Carbamazepine, Lamotrigine, and Levetiracetam on Vascular Risk Markers and Lipid-Lowering Agents in the Elderly Comment by William H. Theodore MD 9 Association of Concomitant Use of Cholinesterase Inhibitors or Memantine With Cognitive Decline in Clinical Trials of Alzheimer’s Disease Comment by Irene Mace Hamrick MD, FAAFP, AGSF 10 Stiripentol Decreases Seizure Frequency in Dravet Syndrome

Nonepileptic Seizures By Barbara Ann Dworetzky MD

14 Generalized Polyspike Train as EEG Biomarker of Drug-Resistant Idiopathic Generalized Epilepsy 15 Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Associated With Antiepileptic Drugs 15 Management of Antiplatelet Therapy in Patients Undergoing Neuroendovascular Procedures 16 Treatment Effect in Cerebrotendinous Xanthomatosis Depends on Age at Start of Treatment Comment by Shuke Nie MD, PhD 17 Novel Method to Distinguish Convulsive Epileptic and Psychogenic Nonepileptic Seizures

22 Young-Onset Multiple System Atrophy By Sonja W. Scholz MD, PhD

11 Stroke Outcomes and Anticoagulation Strategies 11 Statin-Associated Muscle Disease

VOL. 4 • NO. 1 • 2019