Haematology & Oncology News

Kidney failure contributes to 8-18% of PNH related deaths 2,3

• The complement-mediated haemolysis characteristic of PNH leads to cell-free plasma haemoglobin and, as a result, damage to patients’ kidneys 2,4,5 • Kidney failure is the cause of 8-18% of PNH-related deaths 2,3 With early treatment, renal function improvement or stabilisation was achieved in 93.1% of PNH patients 5

The early diagnosis and treatment of PNH helps save lives 2,5 To find out more phone 1800 788 189 or visit identifyingpnh.com.au

PNH = Paroxysmal Nocturnal Haemoglobinuria. References: 1. Dacie JV, Lewis SM. Ser Haematol 1972; 5: 3–23. 2. Hillmen P, et al. Am J Hematol. 2010;85(8):553-559. 3. Nishimura J et al. Medicine (Baltimore) 2004; 83: 193–207. 4. Rother RP et al. JAMA 2005; 293: 1653–1662. 5. Hillmen P, et al. Br J Haematol. 2013;162(1):62-73. © 2016 Alexion Pharmaceuticals Australasia Pty Limited. All rights reserved. Alexion Pharmaceuticals Australasia Pty Limited. ACN 132 343 036. Suite 401, Level 4, Building A, 20 Rodborough Rd, Frenchs Forest. NSW 2086 Australia. May 2016. AU/UNB-PNH/15/0001.